Organogenetic tolerance
نویسندگان
چکیده
منابع مشابه
Organogenetic tolerance.
Transplantation therapy for humans is limited by insufficient availability of donor organs and outcomes are complicated by the toxicity of immunosuppressive drugs. Xenotransplantation is a strategy to overcome supply problems. Implantation of tissue obtained early during embryogenesis is a way to reduce immunogenicity of transplants. Insulin-producing cells originating from embryonic pig pancre...
متن کاملA rapid in vivo assay system for analyzing the organogenetic capacity of human kidney cells.
Transplantation of human kidney-derived cells is a potential therapeutic modality for promoting regeneration of diseased renal tissue. However, assays that determine the ability of candidate populations for renal cell therapy to undergo appropriate differentiation and morphogenesis are limited. We report here a rapid and humane assay for characterizing tubulogenic potency utilizing the well-est...
متن کاملJAK/STAT and Hox Dynamic Interactions in an Organogenetic Gene Cascade
Organogenesis is controlled by gene networks activated by upstream selector genes. During development the gene network is activated stepwise, with a sequential deployment of successive transcription factors and signalling molecules that modify the interaction of the elements of the network as the organ forms. Very little is known about the steps leading from the early specification of the cells...
متن کاملEmbryotoxic and Teratogenic Effects of Nickel in Swiss Albino Mice during Organogenetic Period
The present study evaluates potential hazardous of nickel (Ni(+2) as NiCl2 ·6H2O) to Swiss albino mice fetus. Ni was administered orally on body weight base from days 6 to 13 of gestation period. Based on LD50, Ni doses (46.125, 92.25, and 184.5) mg Ni/kg b.wt. were used. On day 18 of gestation, uteri of the sacrificed dams were examined. A dose-dependent decrease (P < 0.01) in the body weight ...
متن کاملMaximum Tolerance and Maximum Greatest Tolerance
An important consideration when applying neural networks is the sensitivity to weights and threshold in strict separating systems representing a linearly separable function. Two parameters have been introduced to measure the relative errors in weights and threshold of strict separating systems: the tolerance and the greatest tolerance. Given an arbitrary separating system we study which is the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Organogenesis
سال: 2010
ISSN: 1547-6278,1555-8592
DOI: 10.4161/org.6.4.13283